• Maerker et al. Michael Harding Artist Oil Colours, Indian Yellow, 40ml Tube, 20 show that pkd2-mediated post-transcriptional repression dand5 through bicc1 and dicer is a central process in symmetry breaking. Ciliary activity of the calcium channel Pkd2 is crucial for asymmetric leftward flow sensing at the vertebrate left-right organizer.

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  • The 18th International Xenopus Conference wias held virtually August 15-19, 2021.

    Content for registrants will be available until Friday, September 17, 2021.

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    Congratulations to Helen Willsey and Alice Godden named John Gurdon outstanding speaker award winners!

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  • Animal interphase chromosomes are organized into topologically associating domains (TADs). Niu et al. show that X. tropicalis is a powerful model for chromosome architecture analysis suggesting that chromatin remodeling plays an essential role in de novo TAD establishment. Published in Nature Genetics.

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  • Krneta-Stankic et al. show that the Wnt/PCP formin Daam1 regulates cytoskeletal membrane dynamics and E-cadherin localization within developing nephrons.

     

    Published in Cell Reports.

     

     

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  • Social distancing is no mystery to Xenopus cells! Chuyen et al. report how thousands of multiciliated cells distribute into a regular pattern in the developing epidermis, through homotypic repulsion and homing at intercalation sites. Published in Developmental Cell.

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  • The latest release of Xenbase includes the ability to search for Phenotypes.

     

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    Click here to find details on executing a Phenotype search.

     

    Click here to find details on the Xenopus Phenotype Ontology (XPO).

     

     

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  • - available to BLAST

    - view on JBrowse

     

    99.86% of the genome mapped to chromosomes
    ~4500 new and refined models, 18% not present in trop v9.1

     

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  • Maerker et al. LIVE TARGET Hollow Body Mouse 3 1/2" show that pkd2-mediated post-transcriptional repression dand5 through bicc1 and dicer is a central process in symmetry breaking. Ciliary activity of the calcium channel Pkd2 is crucial for asymmetric leftward flow sensing at the vertebrate left-right organizer.

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